p53, phosphorylated (Ser392) (Tumor Suppressor Protein, Oncogene Protein) Antibody
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Catalog numberGEN633372
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PricePlease ask
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Size100ug
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Also known asp53
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Other namesP53; Cellular tumor antigen p53; cellular tumor antigen p53; antigen NY-CO-13; OTTHUMP00000221333; OTTHUMP00000221334; OTTHUMP00000221336; OTTHUMP00000221337; OTTHUMP00000221340; phosphoprotein p53; p53 tumor suppressor; transformation-related protein 53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameTP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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Gene name synonimsTP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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Other gene namesTP53; TP53; P53; LFS1; TRP53; FLJ92943; P53
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone3H2806
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human p53, specifically binding only to p53 phosphorylated at the Ser392 residue. Ser392 phosphorylation of p53 has been shown to occur following DNA damage. Phosphorylation of p53 at this site may be mediated the casein kinase 2 (CK2) and also be other phosphorylation mechanisms. In Immunohistochemistry this antibody generally stains 5-10% of cells labelled with antibodies specific for non-phosphorylated p53.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein A affinity chromatography.
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Form AppearanceSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
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ConcentrationN/A
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Storage and shippingStore the antibody at -20 degrees Celsius.
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Tested applicationsWestern Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionKinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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French translationanticorps
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Gene target
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Short namep53, phosphorylated (Ser392) (Tumor Suppressor Protein, Oncogene Protein) Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-p53, phosphorylated (Ser392) (Tumor Suppressor Protein, Oncogene Protein)
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Alternative techniqueantibodies
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Tissuetumor
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MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data