NFkB Repressing Factor (NKRF, ITBA4, NRF)

• Catalog number
  GEN603882
• Price
  Please ask
• Size
  50ug

• Also known as
  NFkB Repressing Factor
• Other names
  NF-kappa-B-repressing factor isoform 2; NF-kappa-B-repressing factor; NF-kappa-B-repressing factor; OTTHUMP00000023906; OTTHUMP00000023907; transcription factor NRF; NFKB repressing factor; Protein ITBA4; Transcription factor NRF
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  NKRF; NKRF; NRF; ITBA4; ITBA4; NRF
• Gene name synonims
  NKRF; NKRF; NRF; ITBA4; ITBA4; NRF
• Other gene names
  NKRF; NKRF; NRF; ITBA4; ITBA4; NRF
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  8J130
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human NFkB Repressing Factor.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, 1% BSA and 0.05% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Gel Shift Assay (GS/EMSA)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Gene
  NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory

• Gene target
  NFkB   Repressing   Factor   NKRF   ITBA4   NRF  
• Gene symbol
  NKRF, NFE2L2, NFE2L1
• Short name
  NFkB Repressing Factor (NKRF, ITBA4, NRF)
• Alternative name
  Anti-NFkB Repressing Factor (NKRF, ITBA4, NRF)

Gene info

• Identity
  HGNC:19374
• Gene
  NKRF
• Long gene name
  NFKB repressing factor
• Synonyms gene name
  • NF-kappaB repressing factor
• Synonyms
  • ITBA4
  • NRF
• GenBank acession
  • AJ011812
• Locus
  Xq24
• Discovery year
  2004-11-01
• Entrez gene record
  55922
• Pubmed identfication
  • 10562553
• RefSeq identity
  • NM_017544
• Classification
  • G-patch domain containing
• VEGA ID
  OTTHUMG00000022277
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:7782
• Gene
  NFE2L2
• Long gene name
  NFE2 like bZIP transcription factor 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2)-like 2
  • nuclear factor, erythroid 2-like 2
  • nuclear factor, erythroid 2 like 2
• Synonyms
  • NRF2
  • NRF-2
• Synonyms name
  • NF-E2-related factor 2
• Locus
  2q31.2
• Discovery year
  1994-03-24
• Entrez gene record
  4780
• Pubmed identfication
  • 7937919
• RefSeq identity
  • NM_006164
• Classification
  • Basic leucine zipper proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133620

Gene info

• Identity
  HGNC:7781
• Gene
  NFE2L1
• Long gene name
  NFE2 like bZIP transcription factor 1
• Synonyms gene
  • TCF11
• Synonyms gene name
  • nuclear factor (erythroid-derived 2)-like 1
  • nuclear factor, erythroid 2-like 1
  • NF-E2-related factor 1
  • nuclear factor, erythroid 2 like 1
• Synonyms
  • NRF1
  • LCR-F1
  • FLJ00380
  • NRF-1
• Synonyms name
  • nuclear factor erythroid 2-related factor 1
  • locus control region-factor 1
  • transcription factor 11
• GenBank acession
  • AK090459
• Locus
  17q21.32
• Discovery year
  1994-03-24
• Entrez gene record
  4779
• Pubmed identfication
  • 8248256
  • 9501099
  • 26947393
• RefSeq identity
  • NM_003204
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000178706

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