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Also known as
Myogenin
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Other names
myogenin; Myogenin; myogenin; myogenic factor 4; class C basic helix-loop-helix protein 3; myogenin (myogenic factor 4); Class C basic helix-loop-helix protein 3; bHLHc3; Myogenic factor 4; Myf-4
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
MYOG
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Gene name synonims
N/A
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Other gene names
MYOG; MYOG; MYF4; myf-4; bHLHc3; BHLHC3; MYF4; bHLHc3; Myf-4
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1, kappa + IgG1, kappa
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Clone
MGN185 + F5D
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cat, Pig.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
N/A
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Concentration
N/A
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Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applications
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
