Mouse Monoclonal [clone plpc1] (IgG2a) to Bovine PLP1 / Myelin PLP Antibody

• Catalog number
  GEN245441
• Price
  Please ask
• Size
  50ug

• Also known as
  PLP1 / Myelin PLP
• Other names
  myelin proteolipid protein isoform 1; Myelin proteolipid protein; myelin proteolipid protein; lipophilin; major myelin proteolipid protein; proteolipid protein 1; Lipophilin
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  PLP1
• Gene name synonims
  N/A
• Other gene names
  PLP1; PLP1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20; PLP; PLP
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a
• Clone
  plpc1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Bovine, Human (Homo sapiens), Mammal; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes myelin proteolipid protein (PLP) in many mammalian species. This Recognizes DM20. PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A Purified
• Form Appearance
  PBS, 0.09% sodium azide. Sourced in TCS.
• Concentration
  1 miligram per 1 mililiter
• Storage and shipping
  Keep the antibody refrigerated at +4 degrees Celsius for short periods of time. For longer periods of time, freeze the antibody and keep it at -20 degrees Celsius. Cycles of freeze/thaw may reduce the activity. Store the antibodies in an undiluted form.
• Tested applications
  Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   plpc1]   IgG2a   PLP1   Myelin   PLP  
• Gene symbol
  PLP1, PTHLH, PRDX5
• Short name
  Mouse Monoclonal [clone plpc1] (IgG2a) PLP1 / Myelin PLP Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a
• Species
  Bovine, Bos Taurus genes are available form the Bovine Genome database. Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone plpc1] (IgG2a) to Bovine PLP1 / Myelin PLP
• Alternative technique
  antibodies, murine
• Alternative to gene target
  proteolipid protein 1, GPM6C and HLD1 and MMPL and PLP and PLP/DM20 and PMD and SPG2, PLP1 and IDBG-80835 and ENSG00000123560 and 5354, structural constituent of myelin sheath, Plasma membranes, Plp1 and IDBG-173392 and ENSMUSG00000031425 and 18823, PLP1 and IDBG-633948 and ENSBTAG00000006977 and 281410
• Clone name
  plpc1

Gene info

• Identity
  HGNC:9086
• Gene
  PLP1
• Long gene name
  proteolipid protein 1
• Synonyms gene
  • SPG2
  • PLP
• Synonyms gene name
  • spastic paraplegia 2, uncomplicated
• Synonyms
  • GPM6C
• Synonyms name
  • Pelizaeus-Merzbacher disease
• GenBank acession
  • M27110
• Locus
  Xq22.2
• Discovery year
  2001-06-22
• Entrez gene record
  5354
• VEGA ID
  OTTHUMG00000022111
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:9607
• Gene
  PTHLH
• Long gene name
  parathyroid hormone like hormone
• Synonyms
  • PTHRP
  • HHM
  • PLP
  • PTHR
• Synonyms name
  • osteostatin
  • parathyroid hormone-like hormone preproprotein
  • parathyroid hormone-related protein preproprotein
• Locus
  12p11.22
• Discovery year
  2001-06-22
• Entrez gene record
  5744
• Pubmed identfication
  • 2708388
• RefSeq identity
  • NM_198965
• Classification
  • Receptor ligands
  • Neuropeptides
• VEGA ID
  OTTHUMG00000169221

Gene info

• Identity
  HGNC:9355
• Gene
  PRDX5
• Long gene name
  peroxiredoxin 5
• Synonyms
  • ACR1
  • AOEB166
  • MGC142285
  • PRXV
  • PMP20
  • B166
  • PRDX6
  • PLP
  • SBBI10
  • MGC117264
  • MGC142283
• Synonyms name
  • antioxidant enzyme B166
  • thioredoxin peroxidase PMP20
  • peroxisomal antioxidant enzyme
  • TPx type VI
  • liver tissue 2D-page spot 71B
  • Alu co-repressor 1
• GenBank acession
  • AF197952
• Locus
  11q13.1
• Discovery year
  2000-07-31
• Entrez gene record
  25824
• Pubmed identfication
  • 10514471
  • 10521424
• RefSeq identity
  • NM_181651
• Classification
  • Peroxiredoxins
• VEGA ID
  OTTHUMG00000168805

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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