Mouse Monoclonal [clone 3F12] (IgG2a,k) to Human HER3 / ERBB3 Antibody

• Catalog number
  GEN245813
• Price
  Please ask
• Size
  50ug

• Also known as
  HER3 / ERBB3
• Other names
  receptor tyrosine-protein kinase erbB-3 isoform 1; Receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; human epidermal growth factor receptor 3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; erb-b2 receptor tyrosine kinase 3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  HER3
• Gene name synonims
  ERBB3
• Other gene names
  ERBB3; ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; HER3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a,k
• Clone
  3F12
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human ERBB3; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A Purified
• Form Appearance
  PBS, pH 7.2
• Concentration
  0.5 mg/ml
• Storage and shipping
  Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   3F12]   IgG2a   HER3   ERBB3  
• Gene symbol
  ERBB3
• Short name
  Mouse Monoclonal [clone 3F12] (IgG2a k) HER3 / ERBB3 Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone 3F12] (IgG2a,k) to Human HER3 / ERBB3
• Alternative technique
  antibodies, murine
• Alternative to gene target
  v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655
• Clone name
  3F12

Gene info

• Identity
  HGNC:3431
• Gene
  ERBB3
• Long gene name
  erb-b2 receptor tyrosine kinase 3
• Synonyms gene
  • LCCS2
• Synonyms gene name
  • lethal congenital contracture syndrome 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
• Synonyms
  • HER3
• Synonyms name
  • human epidermal growth factor receptor 3
• GenBank acession
  • M34309
• Locus
  12q13.2
• Discovery year
  1990-07-15
• Entrez gene record
  2065
• RefSeq identity
  • NM_001982
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000170140
• Locus Specific Databases
  • LRG_996

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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