Mouse Monoclonal [clone 3F1] (IgG2a,k) to Human HTT / Huntingtin Antibody

• Catalog number
  GEN246499
• Price
  Please ask
• Size
  50ug

• Also known as
  HTT / Huntingtin
• Other names
  huntingtin; Huntingtin; huntingtin; huntington disease protein; huntingtin; Huntington disease protein; HD protein
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  HTT
• Gene name synonims
  N/A
• Other gene names
  HTT; HTT; HD; IT15; HD; IT15; HD protein
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a,k
• Clone
  3F1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human Huntingtin; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A Purified
• Form Appearance
  PBS, pH 7.2
• Concentration
  0.48 mg/ml
• Storage and shipping
  Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   3F1]   IgG2a   HTT   Huntingtin  
• Gene symbol
  HTT-AS, SLC6A4, HTT
• Short name
  Mouse Monoclonal [clone 3F1] (IgG2a k) HTT / Huntingtin Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone 3F1] (IgG2a,k) to Human HTT / Huntingtin
• Alternative technique
  antibodies, murine
• Alternative to gene target
  huntingtin, HD and IT15, HTT and IDBG-7852 and ENSG00000197386 and 3064, diazepam binding, nuclei, Htt and IDBG-156033 and ENSMUSG00000029104 and 15194, HTT and IDBG-643549 and ENSBTAG00000001506 and 615059
• Clone name
  3F1

Gene info

• Identity
  HGNC:37118
• Gene
  HTT-AS
• Long gene name
  HTT antisense RNA
• Synonyms gene
  • HTT-AS1
• Synonyms gene name
  • HTT antisense RNA 1 (non-protein coding)
  • HTT antisense RNA 1
  • HTT antisense RNA (head to head)
• Synonyms
  • HTTAS
• Locus
  4p16.3
• Discovery year
  2011-06-30
• Entrez gene record
  100750326
• Pubmed identfication
  • 21672921
  • 23756188
• RefSeq identity
  • NR_045414
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000159915

Gene info

• Identity
  HGNC:11050
• Gene
  SLC6A4
• Long gene name
  solute carrier family 6 member 4
• Synonyms gene
  • HTT
  • OCD1
• Synonyms gene name
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • 5-hydroxytryptamine (serotonin) transporter
  • obsessive-compulsive disorder 1
  • solute carrier family 6 (neurotransmitter transporter), member 4
• Synonyms
  • 5-HTT
  • SERT1
• Synonyms name
  • serotonin transporter 1
• GenBank acession
  • L05568
• Locus
  17q11.2
• Discovery year
  1994-03-16
• Entrez gene record
  6532
• Pubmed identfication
  • 7681602
  • 19806148
• RefSeq identity
  • NM_001045
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000132751

Gene info

• Identity
  HGNC:4851
• Gene
  HTT
• Long gene name
  huntingtin
• Synonyms gene
  • HD
• Synonyms gene name
  • huntingtin (Huntington disease)
• Synonyms
  • IT15
• GenBank acession
  • L12392
• Locus
  4p16.3
• Discovery year
  1986-01-01
• Entrez gene record
  3064
• Pubmed identfication
  • 8458085
• RefSeq identity
  • NM_002111
• Classification
  • Receptor ligands
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000159916
• Locus Specific Databases
  • LRG_763

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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