Mouse Monoclonal [clone 10-1-62] (IgG) to Human CASP7 / Caspase 7 Antibody
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Catalog numberGEN245844
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PricePlease ask
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Size50ug
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Also known asCASP7 / Caspase 7
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Other namescaspase-7 isoform alpha; Caspase-7; caspase-7; apoptotic protease MCH-3; ICE-like apoptotic protease 3; caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameCASP7
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Gene name synonimsN/A
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Other gene namesCASP7; CASP7; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; MCH3; CASP-7; ICE-LAP3
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG
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Clone22920
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Host organismMouse (Mus musculus)
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Species reactivityHamster, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityDetects an ~37 kD protein, corresponding to the apparent molecular mass of the caspase-7 on SDS-PAGE immunoblots, in samples from human, mouse, rat, monkey and hamster origins. This antibody recognizes recombinant caspase-7 as well as full length pro-caspase-7 and processed enzyme from apoptotic Jurkat cell lysates.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodProtein G Purified
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Form AppearancePBS (10 mM sodium phosphate, pH 7.2, 50 mM sodium chloride, 0.1 mM PMSF)
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ConcentrationN/A
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Storage and shippingStore at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody. For maximum product recovery, after thawing, centrifuge the product vial before removing cap.
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Tested applicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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DescriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolIGHVII-62-1, CASP7, IGLV1-62, IGHV3-62, PIRC49, SNORD115-10, SNORD116-10, IGHD3-10
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Short nameMouse Monoclonal [clone 10-1-62] (IgG) CASP7 / Caspase 7 Antibody
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TechniqueMouse monoclonal, Antibody, Mouse, IgG, antibodies against human proteins, antibodies for, IgGs, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG, IgG
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-Mouse Monoclonal [clone 10-1-62] (IgG) to Human CASP7 / Caspase 7
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Alternative techniqueantibodies, murine, immunoglobulins
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Alternative to gene targetcaspase 7, apoptosis-related cysteine peptidase, CASP-7 and CMH-1 and ICE-LAP3 and LICE2 and MCH3, CASP7 and IDBG-90066 and ENSG00000165806 and 840, cysteine-type endopeptidase activity involved in apoptotic process, nuclei, Casp7 and IDBG-178813 and ENSMUSG00000025076 and 12369, BT.62821 and IDBG-639904 and ENSBTAG00000006615 and 526279
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Clone name10-1-62
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Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-62-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-62-1
- immunoglobulin heavy variable (II)-62-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 1-62 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable 1-62
- immunoglobulin lambda variable 1-62 pseudogene
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-62 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable 3-62
- immunoglobulin heavy variable 3-62 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 49
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy diversity 3-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495
