MOUSE Anti-YERSINIA PESTIS V ANTIGEN Antibody
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Catalog number
GEN214585
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Price
Please ask
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Size
200ug
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Also known as
YERSINIA PESTIS V ANTIGEN
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Other names
secreted effector protein; Virulence-associated V antigen; secreted effector protein; N/A; Low calcium response locus protein V
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
lcrV; lcrV; N/A; icrV
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Gene name synonims
lcrV; lcrV; N/A; icrV
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Other gene names
lcrV; lcrV; N/A; icrV
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
Va13
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Host organism
Mouse (Mus musculus)
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Species reactivity
Bacterial; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
YERSINIA PESTIS V ANTIGEN This item recognises the V antigen of Yersinia pestis (also known as LcrV), a 327-residue soluble protein. Yersinia pestis is a Gram-negative bacillus belonging to the family Enterobacteriaceae. Infection in humans can take the form of bubonic, pneumonic and septicemic plague amongst other less common forms. All three forms have been known for very high mortalitly rates during several epidemics across the world, possibly including the Black Death that ravaged Europe from 1347-1353. Although such large epidemics have not been seen since the Great Plague of London in 1665-1666, the disease still exists and there is concern as to its use as a biological weapon. _x000D__x000D_The V antigen has many complex functions. It mediates the delivery of toxins into host cell, can stimulate production of interleukin-10 (an immunosuppressive cytokine) and it can inhibit chemotaxis of polymorphonuclear neutrophils. Antibodies against LcrV protect against the plague._x000D__x000D_; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 1.0mg/ml
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Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applications
ELISA (EIA), Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Antigens are peptides or recombinant or native dependent on the production method.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Short name
MOUSE Anti-YERSINIA PESTIS V ANTIGEN Antibody
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Technique
Antibody, antigen, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antigenes, mouses
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Anti-MOUSE ANTI YERSINIA PESTIS V ANTIGEN
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Alternative technique
antibodies, antigenes, murine
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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