MOUSE Anti-RAT TCR ALPHA/BETA:Low Endotoxin Antibody

• Catalog number
  GEN211259
• Price
  Please ask
• Size
  500ug

• Also known as
  TCR ALPHA/BETA
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TCR ALPHA/BETA
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  R73
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  TCR ALPHA/BETA This item recognises a constant determinant on the beta chain of the rat alpha/beta T cell receptor, expressed by 97% of peripheral rat T cells as defined by the OX-52 marker. Clone R73 is mitogenic for unseparated spleen cells and for purified T cells. In the rat thymus, mature medullary cells express the R73 determinant at the same levels as peripheral T cells, whereas 94% of CD4 - CD8 - thymocytes are R73 negative. This clone is reported to stimulate adhesion between Thymic Dendritic Cells and Thymocytes; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Low Endotoxin (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0 mg/ml
• Storage and shipping
  Store at -20 degree only. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
• Tested applications
  Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Functional Assay (FA)
• Description
  The MOUSE Anti- TCR ALPHA/BETA: Endotoxin Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• French translation
  anticorps

• Gene target
  TCR   ALPHA/BETA   Endotoxin  
• Gene symbol
  PIAS2, PGLYRP2, SRPRA, CBX5, KCNMB1, AGPAT1, FGF1, DRAP1, DNAJC5B, NAPB
• Short name
  MOUSE Anti- TCR ALPHA/BETA: Endotoxin Antibody
• Technique
  Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
• Host
  mouse
• Species
  Rat, Mouses, Rats
• Alternative name
  Anti-MOUSE ANTI RAT TCR ALPHA/BETA:Low Endotoxin
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:17311
• Gene
  PIAS2
• Long gene name
  protein inhibitor of activated STAT 2
• Synonyms
  • PIASX-BETA
  • miz
  • PIASX-ALPHA
  • ZMIZ4
  • ARIP3
• Synonyms name
  • zinc finger, MIZ-type containing 4
• GenBank acession
  • AF077953
• Locus
  18q21.1
• Discovery year
  2004-06-02
• Entrez gene record
  9063
• Pubmed identfication
  • 9724754
  • 9256341
• RefSeq identity
  • NM_004671
• Classification
  • Zinc fingers MIZ-type
• VEGA ID
  OTTHUMG00000179301

Gene info

• Identity
  HGNC:30013
• Gene
  PGLYRP2
• Long gene name
  peptidoglycan recognition protein 2
• Synonyms
  • PGRP-L
  • PGLYRPL
  • TAGL-like
  • tagL
  • tagL-alpha
  • tagl-beta
  • PGRPL
• Synonyms name
  • peptidoglycan recognition protein L precursor
  • peptidoglycan recognition protein-like
  • N-acetylmuramoyl-L-alanine amidase
• GenBank acession
  • AY358156
• Locus
  19p13.12
• Discovery year
  2004-03-17
• Entrez gene record
  114770
• Pubmed identfication
  • 11461926
  • 12669421
  • 14506276
• RefSeq identity
  • NM_052890
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000150690

Gene info

• Identity
  HGNC:11307
• Gene
  SRPRA
• Long gene name
  SRP receptor subunit alpha
• Synonyms gene
  • SRPR
• Synonyms gene name
  • signal recognition particle receptor (docking protein)
• Synonyms
  • SRP-alpha
  • Sralpha
  • SR-alpha
• GenBank acession
  • BC001162
• Locus
  11q24.2
• Discovery year
  2001-06-22
• Entrez gene record
  6734
• Pubmed identfication
  • 3340536
  • 1312991
• RefSeq identity
  • NM_003139
• VEGA ID
  OTTHUMG00000165826

Gene info

• Identity
  HGNC:1555
• Gene
  CBX5
• Long gene name
  chromobox 5
• Synonyms gene name
  • chromobox homolog 5 (Drosophila HP1 alpha)
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila)
  • chromobox homolog 5
• Synonyms
  • HP1Hs-alpha
  • HP1
  • HP1-ALPHA
• Synonyms name
  • HP1 alpha homolog (Drosophila)
• GenBank acession
  • U26311
• Locus
  12q13.13
• Discovery year
  1999-10-12
• Entrez gene record
  23468
• Pubmed identfication
  • 8663349
• RefSeq identity
  • NM_012117
• Classification
  • Chromobox family
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169700

Gene info

• Identity
  HGNC:6285
• Gene
  KCNMB1
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 1
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1
  • potassium channel subfamily M regulatory beta subunit 1
• Synonyms
  • hslo-beta
• Synonyms name
  • BK channel beta subunit 1
  • MaxiK channel beta-subunit 1
  • big potassium channel beta subunit 1
• GenBank acession
  • AF035046
• Locus
  5q35.1
• Discovery year
  1997-12-05
• Entrez gene record
  3779
• Pubmed identfication
  • 8799178
  • 9888999
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000130439

Gene info

• Identity
  HGNC:324
• Gene
  AGPAT1
• Long gene name
  1-acylglycerol-3-phosphate O-acyltransferase 1
• Synonyms gene name
  • 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
• Synonyms
  • LPAAT-alpha
• Synonyms name
  • lysophosphatidic acid acyltransferase, alpha
• GenBank acession
  • U56417
• Locus
  6p21.32
• Discovery year
  1999-12-07
• Entrez gene record
  10554
• Pubmed identfication
  • 9461603
  • 9291118
• RefSeq identity
  • NM_006411
• Classification
  • MicroRNA protein coding host genes
  • 1-acylglycerol-3-phosphate O-acyltransferases
• VEGA ID
  OTTHUMG00000031210

Gene info

• Identity
  HGNC:3665
• Gene
  FGF1
• Long gene name
  fibroblast growth factor 1
• Synonyms gene
  • FGFA
• Synonyms gene name
  • fibroblast growth factor 1 (acidic)
• Synonyms
  • AFGF
  • ECGF
  • ECGFA
  • ECGFB
  • HBGF1
  • ECGF-beta
  • FGF-alpha
  • GLIO703
• Synonyms name
  • heparin-binding growth factor 1
  • endothelial cell growth factor, alpha
  • endothelial cell growth factor, beta
• GenBank acession
  • X59065
• Locus
  5q31.3
• Discovery year
  1986-01-01
• Entrez gene record
  2246
• Pubmed identfication
  • 1697263
  • 3523756
• RefSeq identity
  • NM_000800
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000059703

Gene info

• Identity
  HGNC:3019
• Gene
  DRAP1
• Long gene name
  DR1 associated protein 1
• Synonyms
  • NC2-alpha
• Synonyms name
  • negative cofactor 2 alpha
  • DR1-associated corepressor
• GenBank acession
  • U41843
• Locus
  11q13.1
• Discovery year
  1998-09-22
• Entrez gene record
  10589
• Pubmed identfication
  • 8608938
• RefSeq identity
  • NM_006442
• VEGA ID
  OTTHUMG00000166723

Gene info

• Identity
  HGNC:24138
• Gene
  DNAJC5B
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5 beta
• Synonyms gene name
  • DnaJ (Hsp40) homolog, subfamily C, member 5 beta
• Synonyms
  • MGC26226
  • CSP-beta
• GenBank acession
  • AF368276
• Locus
  8q13.1
• Discovery year
  2004-03-16
• Entrez gene record
  85479
• Pubmed identfication
  • 29182667
• RefSeq identity
  • NM_033105
• Classification
  • DNAJ (HSP40) heat shock proteins
• VEGA ID
  OTTHUMG00000164470

Gene info

• Identity
  HGNC:15751
• Gene
  NAPB
• Long gene name
  NSF attachment protein beta
• Synonyms gene name
  • N-ethylmaleimide-sensitive factor attachment protein, beta
• Synonyms
  • SNAP-BETA
  • SNAPB
• Synonyms name
  • beta soluble NSF attachment protein
• GenBank acession
  • AK022817
• Locus
  20p11.21
• Discovery year
  2001-05-30
• Entrez gene record
  63908
• Pubmed identfication
  • 8455721
• RefSeq identity
  • NM_022080
• VEGA ID
  OTTHUMG00000032062

MeSH Data

• Name
  Limulus Test
• Concept
  Scope note: Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
• Tree numbers
  • E01.370.225.124.470
  • E01.370.225.875.150.570
  • E05.091.570
  • E05.200.124.470
  • E05.200.875.150.570
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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