MOUSE Anti-HUMAN PROLYL HYDROXYLASE 1 Antibody
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Catalog numberGEN219458
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Price:
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Size100ug
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Also known asPROLYL HYDROXYLASE 1
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Other namesegl nine homolog 2; Egl nine homolog 2; egl nine homolog 2; estrogen-induced tag 6; HIF-prolyl hydroxylase 1; hypoxia-inducible factor prolyl hydroxylase 1; prolyl hydroxylase domain-containing protein 1; egl nine homolog 2 (C. elegans); Estrogen-induced tag 6; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 1; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; Prolyl hydroxylase domain-containing protein 1
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameEGLN2; EGLN2; EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1; EIT6; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; PHD1
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Gene name synonimsEGLN2; EGLN2; EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1; EIT6; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; PHD1
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Other gene namesEGLN2; EGLN2; EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1; EIT6; HIF-PH1; HIF-prolyl hydroxylase 1; HPH-1; PHD1
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ClonalityMonoclonal
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Immunoglobulin isotypeIgM
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ClonePHD112/G7
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityPROLYL HYDROXYLASE 1 This item recognises human prolyl hydroxylase 1 (PHD1), a 44kDa enzyme expressed abundantly in all tissues with the highest expression in testis. _x000D__x000D_Hypoxia inducible factor-1 (HIF-1) is a transcriptional complex, consisting of an alpha and beta subunit, which plays a key role in coordinating the cellular response to hypoxia. During normal oxygen conditions, the alpha subunit of HIF-1 is rapidly degraded, however when hypoxia occurs this degradation is suppressed and HIF-1 activates the transcription of various genes important for survival and adaptation to hypoxia. Prolyl hydroxylase 1 catalyses the hydroxylation of specific prolyl residues within the HIF-1 alpha subunit, thereby targeting this subunit for degradation. _x000D__x000D_Prolyl hydroxylase 1 might also play a role in the regulation of cell growth.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearancePurified (Purified IgG - liquid)
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ConcentrationIgG concentration 1.0mg/ml
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Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from the date of dispatch.
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Tested applicationsWestern Blot (WB), Immunohistology - Paraffin (IHC)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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TestMBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolP4HA1, P4HB, P3H2
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Short nameMOUSE Anti- PROLYL HYDROXYLASE 1 Antibody
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Techniqueanti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
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Hostmouse
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-MOUSE ANTI HUMAN PROLYL HYDROXYLASE 1
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameprolyl 4-hydroxylase subunit alpha 1
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Synonyms gene
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Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I
- prolyl 4-hydroxylase, alpha polypeptide I
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Synonyms
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Synonyms name
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Locus
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Discovery year1999-02-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprolyl 4-hydroxylase subunit beta
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Synonyms gene
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Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase-associated 1)
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
- prolyl 4-hydroxylase, beta polypeptide
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein disulfide isomerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprolyl 3-hydroxylase 2
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Synonyms gene
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Synonyms gene name
- leprecan-like 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2004-05-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Prolyl 3-hydroxylase family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data