-
Also known as
GDF9
-
Other names
growth/differentiation factor 9; Growth/differentiation factor 9; growth/differentiation factor 9; growth differentiation factor 9; N/A
-
Category
Antibodies
-
Subcategory
Mnoclonal antibodies
-
Gene name
GDF9
-
Gene name synonims
N/A
-
Other gene names
Gdf9; Gdf9; Gdf-9; Gdf-9; GDF-9
-
Clonality
Monoclonal
-
Immunoglobulin isotype
IgG
-
Clone
mAb-GDF9-53
-
Host organism
Mouse (Mus musculus)
-
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivity
GDF9 This item recognises an epitope within the highly conserved EPDG sequence of GDF9 (growth differentiation factor 9), a homodimeric growth factor and member of the TGF-beta superfamily, closely related to bone morphogenetic proteins (BMPs). GDF9 is specifically expressed by oocytes, playing a vital role in ovarian folliculogenesis, normal follicle development, and fertility. GDF9 signals through binding to bone morphogenetic protein type II receptor (BMPRII), and apparent subsequent activation of TGF-beta type I receptor, otherwise known as activin receptor-like kinase-5 (ALK-5). Clone mAb-GDF9-53 recognises GDF9 with high immuno-affinity, and has been shown to neutralize GDF9 biological activity Removal of sodium azide is recommended prior to use in functional assays -; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification method
N/A
-
Form Appearance
Purified (Purified IgG - liquid)
-
Concentration
IgG concentration 1.0mg/ml
-
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
-
Tested applications
Functional Assay (FA), Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC), Western Blot (WB)
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus
-
French translation
anticorps
-
Gene target
-
Gene symbol
GDF9
-
Short name
MOUSE Anti- GDF9 Antibody
-
Technique
anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
-
Host
mouse
-
Species
Human, Humans, Mouses
-
Alternative name
Anti-MOUSE ANTI HUMAN GDF9
-
Alternative technique
antibodies, murine
-
Alternative to gene target
growth differentiation factor 9, GDF9 and IDBG-43527 and ENSG00000164404 and 2661, growth factor activity, Extracellular, Gdf9 and IDBG-171675 and ENSMUSG00000018238 and 14566, GDF9 and IDBG-645713 and ENSBTAG00000009478 and 282574
-