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Also known as
DEFENSIN
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Other names
neutrophil defensin 4 preproprotein; Neutrophil defensin 4; neutrophil defensin 4; corticostatin; defensin, alpha 4, preproprotein; defensin, alpha 4, corticostatin; Defensin, alpha 4; HNP-4
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
DEFA4; DEFA4; HP4; DEF4; HP-4; HNP-4; DEF4; HP-4
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Gene name synonims
DEFA4; DEFA4; HP4; DEF4; HP-4; HNP-4; DEF4; HP-4
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Other gene names
DEFA4; DEFA4; HP4; DEF4; HP-4; HNP-4; DEF4; HP-4
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
DEF3
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
DEFENSIN This item recognises human defensin, expressed by mature neutrophils. Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes. DEF-3 recognises alpha defensins (human neutrophil peptides) 1-3. Binding to defensin 4 has not been tested.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - lyophilised)
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Concentration
IgG concentration 0.2 mg/ml after reconstitution.
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Storage and shipping
Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. After reconstitution Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 12 months from date of reconstitution.
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Tested applications
Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC), Western Blot (WB), Flow Cytometry (FACS)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps