Mouse Anti-Human CD40-PE

• Catalog number
  GEN670366
• Price
  Please ask
• Size
  100 Tests

• Also known as
  CD40-PE
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  HB14
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human CD40 CD40, a member of the TNFR-SF, is a 45-48 kDa type I integral membrane glycoprotein whose ligand is CD154. It is expressed on all mature B lymphocytes, but is absent from plasma cells. It is also present on some epithelial and endothelial cells. CD154 binding to CD40 on B cells is important for T cell/B cell interactions and is required for secondary immune responses. Evidence for a role of CD40-CD154 interaction in negative selection and peripheral tolerance has been suggested. CD40 monoclonal antibodies have been reported to stimulate B cell proliferation when costimulated with anti-u, CD20 monoclonal antibodies or phorbol esters.1-3; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  R-phycoerythrin (R-PE) Conjugate
• Concentration
  N/A
• Storage and shipping
  The R-phycoerythrin (R-PE) conjugate is supplied as 100 tests in 2.0 mL of PBS/NaN3 and 0.2% BSA, as a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze!
• Tested applications
  Flow Cytometry, B cell assays
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Latin name
  Mus musculus

• Gene target
  CD40-PE  
• Gene symbol
  ETV3, CD40, ERF
• Short name
  Mouse Anti- CD40-PE
• Technique
  anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, mouses
• Host
  mouse
• Label
  PE
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Anti-Human CD40-PE
• Alternative technique
  murine, antibodies
• Alternative to gene target
  CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849

Gene info

• Identity
  HGNC:3492
• Gene
  ETV3
• Long gene name
  ETS variant transcription factor 3
• Synonyms gene name
  • ets variant gene 3, ETS family transcriptional repressor
  • ETS variant 3
• Synonyms
  • PE-1
• GenBank acession
  • BC022868
• Locus
  1q23.1
• Discovery year
  1994-12-15
• Entrez gene record
  2117
• Pubmed identfication
  • 8020980
• RefSeq identity
  • NM_005240
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000034298

Gene info

• Identity
  HGNC:11919
• Gene
  CD40
• Long gene name
  CD40 molecule
• Synonyms gene
  • TNFRSF5
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 5
  • CD40 molecule, TNF receptor superfamily member 5
• Synonyms
  • p50
  • Bp50
• GenBank acession
  • X60592
• Locus
  20q13.12
• Discovery year
  1993-08-27
• Entrez gene record
  958
• Pubmed identfication
  • 7687385
  • 2998589
• RefSeq identity
  • NM_001250
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000033053
• Locus Specific Databases
  • CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
  • LRG_40

Gene info

• Identity
  HGNC:3444
• Gene
  ERF
• Long gene name
  ETS2 repressor factor
• Synonyms gene name
  • Ets2 repressor factor
• Synonyms
  • PE-2
  • PE2
• GenBank acession
  • U58535
• Locus
  19q13.2
• Discovery year
  1998-07-17
• Entrez gene record
  2077
• Pubmed identfication
  • 7588608
  • 9192842
• RefSeq identity
  • NM_006494
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000182788

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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