MALT1
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Catalog numberGEN438305
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Price:
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Size100ug
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Also known asMALT1
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Other namesmucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT lymphoma-associated translocation; mucosa associated lymphoid tissue lymphoma translocation gene 1; MALT lymphoma-associated translocation; Paracaspase
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameMALT1
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Gene name synonimsN/A
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Other gene namesMALT1; MALT1; MLT; MLT1; IMD12; MLT
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1, kappa
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CloneMT1/410
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityMucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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Gene target
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Gene symbolMALT1-AS1, MALT1
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Short nameMALT1
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Alternative nameAnti-MALT1
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Alternative to gene targetmucosa associated lymphoid tissue lymphoma translocation gene 1, IMD12 and MLT and MLT1, MALT1 and IDBG-3930 and ENSG00000172175 and 10892, protein self-association, nuclei, Malt1 and IDBG-154592 and ENSMUSG00000032688 and 240354, MALT1 and IDBG-644866 and ENSBTAG00000027916 and 504994
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Gene info
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Identity
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Gene
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Long gene nameMALT1 antisense RNA 1
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Locus
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Discovery year2020-10-16
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameMALT1 paracaspase
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Synonyms gene
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Synonyms gene name
- mucosa associated lymphoid tissue lymphoma translocation gene 1
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Synonyms
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Synonyms name
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Locus
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Discovery year1999-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CBM complex
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VEGA ID
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Locus Specific Databases