KSR (Kinase Suppressor of Ras, KSR1, BKSR1, dKsr, EK31, hb, Positive Ras Signaling Mediator Family Member, RSU2, Suppressor of Activated let 60 Ras SUR3, Suppressor of Ras1 31, SR31)
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Catalog numberGEN609206
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PricePlease ask
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Size200ug
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Also known asKSR
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Other nameskinase suppressor of Ras 1; Kinase suppressor of Ras 1; kinase suppressor of Ras 1; kinase suppressor of ras 1; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameKSR1; KSR1; KSR; RSU2; KSR
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Gene name synonimsKSR1; KSR1; KSR; RSU2; KSR
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Other gene namesKSR1; KSR1; KSR; RSU2; KSR
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG
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Clone4i45
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Host organismMouse (Mus musculus)
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Source organismRat (Rattus norvegicus)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes rat KSR, Mr 120kD. Species Crossreactivity: human and mouse; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodAffinity Purified by Protein G affinity chromatography.
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Form AppearanceSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide, before the addition of glycerol to 30%.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
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DescriptionPositive controls are the same as the target vector or antibody or protein and can be spiked to the sample before the analysis starts. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
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Grouppositif
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Gene target
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Gene symbolKSR1, CNKSR1
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Short nameKSR (Kinase Suppressor of Ras, KSR1, BKSR1, dKsr, EK31, hb, Positive Ras Signaling Mediator Family Member, RSU2, Suppressor of Activated let 60 Ras SUR3, Suppressor of Ras1 31, SR31)
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TechniquePositive
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Alternative nameAnti-KSR (Kinase Suppressor of Ras, KSR1, BKSR1, dKsr, EK31, hb, Positive Ras Signaling Mediator Family Member, RSU2, Suppressor of Activated let 60 Ras SUR3, Suppressor of Ras1 31, SR31)
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Alternative techniquecontrols
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Gene info
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Identity
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Gene
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Long gene namekinase suppressor of ras 1
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Synonyms gene
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Synonyms gene name
- kinase suppressor of ras
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-03-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAF family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameconnector enhancer of kinase suppressor of Ras 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-05-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sterile alpha motif domain containing
- PDZ domain containing
- Pleckstrin homology domain containing
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VEGA ID