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Also known as
Integrin alpha 4
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Other names
integrin alpha-4; Integrin alpha-4; integrin alpha-4; 269C wild type; integrin alpha 4; integrin alpha-IV; OTTHUMP00000205320; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D, alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor, alpha 4 subunit; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
ITGA4; ITGA4; IA4; CD49D; MGC90518; CD49D
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Gene name synonims
ITGA4; ITGA4; IA4; CD49D; MGC90518; CD49D
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Other gene names
ITGA4; ITGA4; IA4; CD49D; MGC90518; CD49D
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG
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Clone
9H405
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Host organism
Rabbit (Oryctolagus cuniculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human Integrin alpha4 phosphorylated on Serine 1027 and the mature chain (180kD), the precursor (140kD) and the cleaved C terminal (70kD). Species Crossreactivity: Mouse and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Supernatant
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Form Appearance
Supplied as a liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide, 0.05% BSA.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
Western Blot (WB)
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Description
The Integrin alpha 4, phosphorylated (Ser1027) (CD49d, CDw49d, Integrin alpha IV, IA4, ITGA4, LPAM23, MGC90518, Very Late Activation Protein 4 Receptor Alpha 4 Subunit, VLA4) Antibody is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ITGA4, CD82
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Short name
Integrin alpha 4, phosphorylated (Ser1027) (CD49d, CDw49d, Integrin alpha IV, IA4, ITGA4, LPAM23, MGC90518, Very Late Activation Protein 4 Receptor Alpha 4 Subunit, VLA4) Antibody
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Technique
activation, Antibody, antibodies against human proteins, antibodies for
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Alternative name
Anti-Integrin alpha 4, phosphorylated (Ser1027) (CD49d, CDw49d, Integrin alpha IV, IA4, ITGA4, LPAM23, MGC90518, Very Late Activation Protein 4 Receptor Alpha 4 Subunit, VLA4)
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Alternative technique
antibodies
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Alternative to gene target
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), CD49D and IA4, ITGA4 and IDBG-76684 and ENSG00000115232 and 3676, cell adhesion molecule binding, Cell surfaces, Itga4 and IDBG-183203 and ENSMUSG00000027009 and 16401, ITGA4 and IDBG-639925 and ENSBTAG00000009256 and 282882
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