anti-mouse CD40 mAb CD40-A, purified

Categories

Antibodies
Description

mAb CD40-A is suitable for activation of mouse B cells.
Recommandation

The monoclonal antibody is supplied in PBS without preservatives. Endotoxin content is below 10 EU/mg.
Antibody Clone

CD40-A
Enzyme Conjugate

unconjugated
Format

purified
Application

Cell stimulation
Reactivities

mouse
Analytes

CD40
Specificity

CD40
Contents

CD40-A, purified, supplied at 0.5 mg/ml in sterile filtered PBS free of preservatives
Datasheet
Product Header

Monoclonal antibody specific for CD40
Shelf Life

18 months
Additional description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

CD40 mAb CD40-A
Gene symbol

CD40, HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1, LINC01139, FABP4
Short name

anti-mouse CD40 mAb CD40-A, purified
Technique

purified, anti-, Mouse, anti, antibody to, antibodies, mouses, purifications
Host

Rat
Isotype

IgG2a
Species

Mouse, Mouses
Alternative name

Antibody tomouse CD40 molecule, tumor necrosis factor receptor superfamily member 5 monoclonal CD40 molecule, tumor necrosis factor receptor superfamily member 5-A, enriched
Alternative technique

pure, murine, antibodies
Alternative to gene target

CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849

Identity

HGNC:11919
Gene

CD40
Long gene name

CD40 molecule
Synonyms gene
- TNFRSF5
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 5
- CD40 molecule, TNF receptor superfamily member 5
Synonyms
- p50
- Bp50
GenBank acession
- X60592
Locus

20q13.12
Discovery year

1993-08-27
Entrez gene record

958
Pubmed identfication
- 7687385
- 2998589
RefSeq identity
- NM_001250
Classification
- CD molecules
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000033053
Locus Specific Databases
- CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base)
- LRG_40

Identity

HGNC:5661
Gene

IGHV5-10-1
Long gene name

immunoglobulin heavy variable 5-10-1
Synonyms gene
- IGHV5-A
Synonyms gene name
- immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
- immunoglobulin heavy variable 5-A (provisional)
Synonyms
- IGHV5-a
GenBank acession
- X92227
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28386
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000191143

Identity

HGNC:10289
Gene

RPA1
Long gene name

replication protein A1
Synonyms gene name
- replication protein A1 (70kD)
- replication protein A1, 70kDa
Synonyms
- REPA1
- RPA70
- HSSB
- RF-A
- RP-A
GenBank acession
- M63488
Locus

17p13.3
Discovery year

1993-12-14
Entrez gene record

6117
Pubmed identfication
- 8454588
RefSeq identity
- NM_002945
Classification
- Nucleotide excision repair
VEGA ID

OTTHUMG00000090579

Identity

HGNC:34406
Gene

CDC37P1
Long gene name

cell division cycle 37 pseudogene 1
Synonyms gene name
- cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
Synonyms
- A-761H5.2
Locus

16p11.2
Discovery year

2009-01-29
Entrez gene record

390688
Pubmed identfication
- 15616553
RefSeq identity
- NG_009463
VEGA ID

OTTHUMG00000175739

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data