anti-human/monkey TNF-alpha mAb MT15B15, PF488P
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Catalog number
3512M-71-100T
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Price
Please ask
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Size
100 tests
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Categories
Antibodies
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Description
This monoclonal antibody enables sensitive and specific detection of TNF-α producing cells in flow cytometry.
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Recommandation
Ready-to-use solution of PF488P-conjugated mAb MT15B15.
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Antibody Clone
MT15B15
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Enzyme Conjugate
PF488P
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Format
fluorophore-conjugated
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Application
Flow cytometry
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Reactivities
non-human primates
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Analytes
TNFA
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Specificity
Native and recombinant TNF-α
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Contents
MT15B15, PF488P-conjugated, ready-to-use in PBS with 0.2% BSA and 0.09% sodium azide
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Product Header
Monoclonal antibody specific for TNF-α
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GeneID
The monoclonal antibody reacts with human TNF-α and cross-react with TNF-α from non-human primates.
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Shelf Life
18 months
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Additional description
The anti- / TNF-alpha mAb MT15B15, PF488P is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Rhesus Monkeys proteins are often measured by ELISA on serum or plasma since consensus epitopes with the human ELISA are used for producing the antibodies of these ELISA test kits. Often cDNA of monkeys is used as alternative to human cDNA as a model for drug development. Monkeys are generally considered to be intelligent, particularly Old World monkeys.
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Test
Mabtech supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
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Short name
anti- / TNF-alpha mAb MT15B15, PF488P
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Technique
anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
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Host
Mouse
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Isotype
IgG1
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Species
Monkey, Humans, Monkeys
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Alternative name
Antibody tohuman/monkey tumor necrosis factor-a monoclonal MT15B15, PF488P
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Alternative technique
antibodies
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Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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