Human Inter- alpha- trypsin inhibitor heavy chain H4, ITIH4 ELIS

Description

The Inter- alpha- trypsin inhibitor heavy chain H4, ITIH4 ELIS is a α- or alpha protein sometimes glycoprotein present in blood. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

Inter alpha trypsin inhibitor heavy chain ITIH4 ELIS
Gene symbol

ITIH4-AS1, ITIH4
Short name

Inter- alpha- trypsin inhibitor heavy chain H4, ITIH4 ELIS
Species

Human, Humans
Alternative name

H. sapiens Inter- a- trypsin suppressor heavy epitope H4, inter-alpha-trypsin inhibitor heavy chain family, member 4 ELIS
Alternative to gene target

inter-alpha-trypsin inhibitor heavy chain family, member 4, GP120 and H4P and IHRP and ITI-HC4 and ITIHL1 and PK-120 and PK120, ITIH4 and IDBG-39759 and ENSG00000055955 and 3700, protein binding, Extracellular, Itih4 and IDBG-143373 and ENSMUSG00000021922 and 16427, ITIH4 and IDBG-645479 and ENSBTAG00000007850 and 513700

Identity

HGNC:6169
Gene

ITIH4
Long gene name

inter-alpha-trypsin inhibitor heavy chain 4
Synonyms gene
- ITIHL1
Synonyms gene name
- inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
- inter-alpha-trypsin inhibitor heavy chain family, member 4
Synonyms
- IHRP
- H4P
Synonyms name
- plasma Kallikrein-sensitive glycoprotein
GenBank acession
- D38535
Locus

3p21.1
Discovery year

1995-11-30
Entrez gene record

3700
Pubmed identfication
- 9480842
- 7805892
RefSeq identity
- NM_002218
Classification
- Inter-alpha-trypsin inhibitor heavy chains
VEGA ID

OTTHUMG00000159023