N-De[2-(methylsulfonyl)ethyl] Lapatinib

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Stock availability

In Stock
Cas number

697299-82-4
Chemical s molecular weight

474.91
Chemical s main applications

A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
Chemical s category

Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Other name

6-[5-(Aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-4-quinazolinamine; [6-(5-Aminomethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]amine;
Chemical s formula

C26H20ClFN4O2
Physical properties

Light Yellow to Light Beige Solid
Melting temperature

>141ºC (dec.)
Boiling temperature

No Data Available
Chemical s soluble in

DMSO (Slightly), Methanol (Slightly, Heated)
Stability conditions

No Data Available
Storage

-20°C Freezer, Under inert atmosphere
Chemical s specifications