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Dexamethasone for cell activation

  • Catalog number
    1042-1G
  • Product name
    Dexamethasone for cell activation
  • Size
    1 g
  • Price
    192.85
  • Supplier
    Biovision
  • Description
    An anti-inflammatory glucocorticoid. Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells (IC₅₀ = 5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexamethasone is sufficient to induce apoptosis following a 6-hour incubation at 37°C
  • Peptide sequence
    N/A
  • CAS number
    50-02-2
  • Molecular weight
    392.46
  • Category
    Apoptosis Inducer
  • Other name
    9α-Fluoro-16α-methylprednisolone, Prednisolone F, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • Molecular formula
    C₂₂H₂₉FO₅
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    >99% by TLC
  • Reconstitute instructions
    DMSO ( 25 mg/ml) or EtOH
  • Storage condition
    -20°C
  • Shipping condition
    RT
  • Maximum time for storage
    12 months
  • Storage instructions
    Protect from light and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Dexamethasone for activation
  • Technique
    activation
  • Alternative name
    Dexamethasone to measure cellular activation
MeSH Data
  • Name
  • Concept
    Registry number:7S5I7G3JQL
    Scope note:An anti-inflammatory 9-fluoro-glucocorticoid.
    CASN1 number:Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-
  • Tree numbers
    • D04.210.500.745.432.769.344
    • D04.210.500.908.238
  • Qualifiers
    analogs & derivatives, immunology, pharmacokinetics, therapeutic use, toxicity, poisoning, administration & dosage, adverse effects, agonists, blood, cerebrospinal fluid, chemical synthesis, contraindications, chemistry, urine, radiation effects, history, analysis, antagonists & inhibitors, classification, economics, isolation & purification, metabolism, pharmacology, standards, supply & distribution
Additional information
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