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Anti-human Fibrinogen (4F7) Monoclonal, ALEXA Fluor 594

  • Catalog number
    GENTObsm-1240M-A594
  • Product name
    Anti-human Fibrinogen (4F7) Monoclonal, ALEXA Fluor 594
  • Size
    117 microliters
  • Price
    489EUR
  • Supplier
    Bioss Monoclonal Antibodies
  • Ask
  • Clonality
    Monoclonal Antibodies
  • Conjugated with
    ALEXA FLUOR 594
  • Gene ID
    2243
  • Cross Reactive species
    Human (Homo sapiens)
  • Cross Reactive Species details
    No significant cross reactivity is observed
  • Synonyms
    FGA; FGA protein; FGB; FGG; Fib2; Fibrin alpha chain ;Fibrinogen A alpha polypeptide; Fibrinogen A alpha polypeptide chain; Fibrinogen alpha chain; Fibrinogen B alpha polypeptide; Fibrinogen beta chain; Fibrinogen G alpha polypeptide; Fibrinogen gamma chain; MGC104327; MGC119422; MGC119423; MGC119425; MGC120405; FIBA_HUMAN.
  • Alternative name 1
    human Fibrinogen (4F7) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
  • Purification method
    Purified by Protein G.
  • Advisory
    Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
  • Storage
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Target Protein/Peptide
    human Fibrinogen
  • Alternative name 2
    human Fibrinogen (4F7) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
  • Modification
    Not modified
  • Host organism
    Mouse (Mus musculus)
  • Background information
    Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
  • Specificity
    Highly specific antibody against human Fibrinogen
  • Applications with corresponding dilutions
    IF(IHC-P)(1:50-200)
  • Clone
    4F7
  • Applications
    IF(IHC-P)
  • Concentration
    1ug per 1ul
  • Type
    Conjugated Primary Antibody
  • Excitation emission
    590nm/617nm
  • Antigen Source
    Fibrinogen from human plasma
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Gene target
  • Short name
    Anti-human Fibrinogen (4F7) Monoclonal, Fluor 594
  • Technique
    Monoclonals or monoclonal antibodies
  • Label
    ALEXA
  • Alternative name
    antibody to-H. sapiens Fibrinogen (4F7) monoclonal, ALEXA Fluor 594
  • Ask
MESH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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