ROR2 Antibody
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Catalog numberF50670-0.08ML
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PricePlease ask
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Size0.08 ml
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CategoryAntibody
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ConcentrationIn 1X PBS, pH 7.4, with 0.09% sodium azide
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FormPurified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenROR2
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC, ELISA
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Recommended dilutionsWestern blot: 1:1000,IHC (Paraffin): 1:10-1:50
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NotesTitration of the ROR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis ROR2 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotQ01974
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PurityPurified
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DescriptionROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.
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ImmunogenThis ROR2 antibody was produced from rabbits immunized with a recombinant protein of human ROR2.
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StorageAliquot the ROR2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolROR2, RORA
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Short nameAnti-ROR2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameAntibodies to ROR2
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namereceptor tyrosine kinase like orphan receptor 2
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Synonyms gene
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Synonyms gene name
- receptor tyrosine kinase-like orphan receptor 2
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GenBank acession
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Locus
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Discovery year2000-02-29
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Entrez gene record
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Pubmed identfication
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Classification
- Receptor tyrosine kinases
- I-set domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameRAR related orphan receptor A
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Synonyms gene name
- RAR-related orphan receptor A
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-04-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAR related orphan receptors
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
