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Target antigen
ROR1
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
rat Predicted to work with: mouse
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Analyses
WB,IHC-P
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ROR1(904-918aa NKSQKPYKIDSKQAS), different from the related rat and mouse sequences by one amino acid.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the ROR1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The ROR1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
ROR1(receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase, receptor-related 1(NTRKR1), Tyrosine-protein kinase transmembrane receptor ROR1, is a member of thereceptor tyrosine kinase-like orphan receptor(ROR) family. NTRKR1 encodes a predicted 937-amino acid protein. A 6-kb NTRKR1 mRNA is expressed strongly in human heart, lung, and kidney, but weakly in the CNS. However, a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. The protein encoded by this gene is a receptor tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors.
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Related articles
1. Reddy, U. R., Phatak, S., Allen, C., Nycum, L. M., Sulman, E. P., White, P. S., Biegel, J. A. Localization of the human Ror1 gene (NTRKR1) to chromosome 1p31-p32 by fluorescence in situ hybridization and somatic cell hybrid analysis.Genomics 41: 283-285, 1997.
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Gene Name
ROR1
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Protein Name
Inactive tyrosine-protein kinase transmembrane receptor ROR1
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Gene Full Name
receptor tyrosine kinase-like orphan receptor 1
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Synonyms
dJ537F10.1 antibody|MGC99659 antibody|Neurotrophic tyrosine kinase antibody|Neurotrophic tyrosine kinase receptor related 1 antibody|Neurotrophic tyrosine kinase, receptor related 1 antibody|NTRKR1 antibody|OTTHUMP00000010573 antibody|OTTHUMP00000010574 antibody|OTTMUSP00000008344 antibody|Receptor tyrosine kinase like orphan receptor 1 antibody|receptor-related 1 antibody|RGD1559469 antibody|ROR 1 antibody|ROR1 antibody|ROR1_HUMAN antibody|RP11 24J23.1 antibody|Ttyrosine protein kinase transmembrane receptor ROR1 antibody|Tyrosine kinase like orphan receptor 1 antibody|Tyrosine protein kinase transmembrane receptor ROR1 antibody|Tyrosine-protein kinase transmembrane receptor ROR1 antibody
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Uniprot ID
Q01973
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
