Rb/P105 RB (Thr821) Antibody, Cy7 Conjugated

  • Catalog number
    bs-3452R-Cy7
  • Product name
    Rb/P105 RB (Thr821) Antibody, Cy7 Conjugated
  • Size
    0.1ml
  • Price
    434.46
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Long name
    Rb/P105 RB (Thr821) Polyclonal Antibody, Cy7 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy7
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Rb/P105 RB Thr821
  • Specificity
    This is a highly specific antibody against Rb/P105 RB Thr821.
  • Modification
    Phosphorylation
  • Modification site
    Thr821
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Thr821
  • Gene ID number
    5925
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    743nm/767nm
  • Synonyms
    OSRC; P105 RB; P105RB; PP105; PP110; pRb; RB 1; RB1; RB1 protein; Retinoblastoma 1 including osteosarcoma; Retinoblastoma 1; Retinoblastoma associated protein; Retinoblastoma related osteosarcoma; Retinoblastoma susceptibility gene; Including osteosarcoma; RB_HUMAN.
  • group_crc32
    2428363312
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugated
    These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
  • Additional conjugation
    Cy7
  • French translation
    anticorps
  • Gene target
  • Short name
    Rb/P105 RB (Thr821) Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
    Cy7
  • Alternative name
    Rb/P105 RB (Thr821) (Antibody to), cyanine 7 coupled
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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Rb/P105 RB (Thr821) Antibody, Cy7 Conjugated - Gentaur.com
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