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PTP1B Antibody, FITC Conjugated

  • Catalog number
    bs-0182R-FITC
  • Product name
    PTP1B Antibody, FITC Conjugated
  • Size
    0.1ml
  • Price
    391.57
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Long name
    PTP1B Polyclonal Antibody, FITC Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    FITC
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    PTP1B
  • Specificity
    This is a highly specific antibody against PTP1B.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen_range
    13-65/435
  • Subcellular location
    Cytoplasm
  • Source
    KLH conjugated synthetic peptide derived from human PTP-1B
  • Gene ID number
    5770
  • Swiss Prot
    P18031
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    494nm/518nm
  • Synonyms
    PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
  • Additional conjugation
    Anti-FITC Antibody
  • French translation
    anticorps
  • Gene target
  • Short name
    PTP1B Antibody, FITC Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
  • Label
    FITC
  • Alternative name
    PTP1B (Antibody to), fluorecein coupled
  • Alternative technique
    antibodies
1. Gene info
  • Identity
  • Gene
  • Long gene name
    protein tyrosine phosphatase, non-receptor type 1
  • Synonyms gene
  • Locus
  • Discovery year
    1991-09-13
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Protein tyrosine phosphatases, non-receptor type
  • Havana BLAST/BLAT
MeSH Data
  • Name
  • Concept
    Scope note:A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
  • Tree numbers
    • E01.370.225.500.386
    • E05.196.712.516.600.240
    • E05.200.500.386
    • E05.242.386
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
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