MAPK6/ERK3 Antibody, Cy5 Conjugated

• Catalog number
  bs-12405R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  MAPK6/ERK3 Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MAPK6/ERK3
• Specificity
  This is a highly specific antibody against MAPK6/ERK3.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human MAPK6/ERK3
• Gene ID number
  5597
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  ERK-3; ERK3; ERK 3; ERK-3; Extracellular signal regulated kinase 3; Extracellular signal regulated kinase p97; Extracellular signal-regulated kinase 3; MAP kinase 6; MAP kinase isoform p97; MAPK 6; MAPK6; Mitogen activated protein kinase 6; Mitogen-activated protein kinase 6; MK06_HUMAN; p97 MAPK; p97-MAPK; PRKM6; Protein kinase mitogen activated 5; Protein kinase mitogen activated 6.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  MAPK6/ERK3   Conjugated  
• Gene symbol
  MAPK6, MAPK6-DT, MAPK4
• Short name
  Anti-MAPK6/ERK3
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-MAPK6/ERK3 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6879
• Gene
  MAPK6
• Long gene name
  mitogen-activated protein kinase 6
• Synonyms gene
  • PRKM6
• Synonyms
  • ERK3
  • p97MAPK
  • HsT17250
• GenBank acession
  • L77964
• Locus
  15q21.2
• Discovery year
  1998-04-28
• Entrez gene record
  5597
• Pubmed identfication
  • 8875998
• RefSeq identity
  • NM_002748
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000131891

Gene info

• Identity
  HGNC:53900
• Gene
  MAPK6-DT
• Long gene name
  MAPK6 divergent transcript
• Synonyms
  • lncMAPK6
• Locus
  15q21.2
• Discovery year
  2018-05-17
• Entrez gene record
  112543478
• Pubmed identfication
  • 29764463
• RefSeq identity
  • NR_156732
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:6878
• Gene
  MAPK4
• Long gene name
  mitogen-activated protein kinase 4
• Synonyms gene
  • PRKM4
• Synonyms
  • Erk3-related
  • Erk4
• GenBank acession
  • X59727
• Locus
  18q21.1-q21.2
• Discovery year
  1993-11-08
• Entrez gene record
  5596
• Pubmed identfication
  • 8290275
• RefSeq identity
  • NM_002747
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000179853

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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