HEXA/Beta hexosaminidase subunit alpha Antibody, Cy5.5 Conjugated

  • Catalog number
  • Product name
    HEXA/Beta hexosaminidase subunit alpha Antibody, Cy5.5 Conjugated
  • Size
  • Price
  • Supplier
    Bioss Primary Conjugated Antibodies
  • Long name
    HEXA/Beta hexosaminidase subunit alpha Antibody, Cy5.5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    HEXA/Beta hexosaminidase subunit alpha
  • Specificity
    This is a highly specific antibody against HEXA/Beta hexosaminidase subunit alpha.
  • Modification
  • Modification site
  • Clonality
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human Beta hexosaminidase subunit alpha
  • Tested applications
  • Recommended dilutions
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
  • Synonyms
    Beta hexosaminidase alpha chain precursor; Beta hexosaminidase subunit alpha; Beta N acetylhexosaminidase; Beta N acetylhexosaminidase subunit alpha; Beta-hexosaminidase subunit alpha; Beta-N-acetylhexosaminidase subunit alpha; Hexa; HEXA_HUMAN; Hexosaminidase A alpha polypeptide; Hexosaminidase A alpha polypeptide; Hexosaminidase A; Hexosaminidase subunit A; MGC99608; N acetyl beta glucosaminidase; N acetyl beta glucosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; TSD.
  • group_crc32
  • Description
    The HEXA/Beta hexosaminidase subunit alpha Antibody, Conjugated is a α- or alpha protein sometimes glycoprotein present in blood.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
    Cy5.5, Cy5.5
  • Conjugated
    These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
  • French translation
  • Gene target
  • Short name
    HEXA/Beta hexosaminidase subunit alpha Antibody, Conjugated
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Label
  • Alternative name
    HEXA/b hexosaminidase functionnal sequence a (Antibody to), cyanine 5.5 coupled
  • Alternative technique
1. Gene info
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
Additional information
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