CACNA1B (N type) Antibody, ALEXA FLUOR 647

  • Catalog number
    bs-10490R-A647
  • Price
    Please ask
  • Size
    100ul
  • Long name
    CACNA1B (N type) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
  • Also known as
    Anti-CACNA1B N type PAb ALEXA FLUOR 647
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 647
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    CACNA1B N type
  • Specificity
    This is a highly specific antibody against CACNA1B N type.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    115-132/2339
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1B (N type)
  • Gene ID Number
    774
  • Swiss Prot
    Q00975
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    650nm/665nm
  • Synonyms
    BIII; CACNN; DYT23; Cav2.2; CACNL1A5; Voltage-dependent N-type calcium channel subunit alpha-1B; Brain calcium channel III; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2; CACNA1B; CACH5
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CACNA1B N type exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 647
  • French translation
    anticorps
  • Gene target
    CACNA1B  
  • Gene symbol
    CACNA1B
  • Short name
    Anti-CACNA1B N type
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 647
  • Alternative name
    CACNA1B (N type) Polyclonal Antibody, ALEXA FLUOR 647
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    calcium voltage-gated channel subunit alpha1 B
  • Synonyms gene
  • Synonyms gene name
    • calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1995-06-01
  • Entrez gene record
    774
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Calcium voltage-gated channel alpha1 subunits
    • EF-hand domain containing
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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