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anti-USP5 Antibody

  • Catalog number
    6132-50
  • Product name
    anti-USP5 Antibody
  • Size
    USP5 Antibody
  • Price
    208EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Chicken
  • This antibody reacts with:
    Human
  • Purification method:
    Purified from egg yolk
  • Immunogene sequence:
    Recombinant full length protein
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    USP5
  • Formulation of this antibody:
    50 µg of antibody in PBS containing 10% glycerol
  • Alternative names of antibody target:
    Deubiquitinating enzyme 5, Isopeptidase T, IsoT, ISOT, Ubiquitin carboxyl-terminal hydrolase 5, Ubiquitin-specific-processing protease 5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5.
  • Recommended usage:
    Western blot: Robust detection of 100 ng of recombinant protein was possible when antibody was used at a final concentration of 5 μg/mL
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Chicken IgG
  • Background information:
    The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP5 (ubiquitin specific peptidase 5), also known as ISOT (isopeptidase T), is a 858 amino acid zinc-binding deubiquitinating enzyme that participates in the Ub pathway. A member of the peptidase C19 family, the catalytic activity of USP5 involves a combination of the ubiquitin carboxyl-terminal thiolester and water to produce ubiquitin and a thiol. USP5 contains two UBA domains and one UBP-type zinc finger. USP5 is responsible for disassembling unanchored polyubiquitin chains in the cell. Full length USP5 mediated cleavage of Ub-PLA2 is significantly enhanced is enhanced by low concentrations of mono ubiquitin.
  • Concentration of antibody:
    N/A
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-USP5 Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-USP5 (Antibody to)
  • Alternative technique
    antibodies
1. Gene info
  • Identity
  • Gene
  • Long gene name
    ubiquitin specific peptidase 5
  • Synonyms gene name
    • ubiquitin specific peptidase 5 (isopeptidase T)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1999-02-01
  • Pubmed identfication
  • Classification
    • Ubiquitin specific peptidases
  • Havana BLAST/BLAT
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