gp120 (C2-94UG114)(HIV-1/Clade D)

Protein group

HIV/SIV Proteins
Product Type

Purified Protein
Applications

WB standard, antibody ELISA, etc
Gene

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. recombinant HIV 1 and 2 gag gene proteins p24, p17, p55 immunodominant epitopes and envelope glycoproteins, gp120 are used for production of diagnostic detection antibodies.

Gene target

gp120 C2-94UG114 HIV-1/Clade
Gene symbol

C2, SNAR-C2, C2-AS1, PCDHAC2, GCNT3, NPC2, PIK3C2B, MAGEC2, HIVEP2, IGHVII-1-1
Short name

gp120 (C2-94UG114)(HIV-1/Clade D)
Alternative name

gp120 (complement component 2-94UG114)(human immunodeficiency virus-1/Clade D)
Alternative to gene target

complement component 2, ARMD14 and CO2, C2 and IDBG-124824 and ENSG00000166278 and 101928623,717, protein binding, Extracellular, C2 and IDBG-174547 and ENSMUSG00000024371 and 12263, C2 and IDBG-633680 and ENSBTAG00000007450 and 515440
Virus

hiv

Identity

HGNC:1248
Gene

C2
Long gene name

complement C2
Synonyms gene name
- complement component 2
Locus

6p21.33
Discovery year

2001-06-22
Entrez gene record

717
Classification
- Complement system activation components
- Sushi domain containing
VEGA ID

OTTHUMG00000031190
Locus Specific Databases
- C2base: Mutation registry for C2 deficiency
- LRG_26

Identity

HGNC:8972
Gene

PIK3C2B
Long gene name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms gene name
- phosphoinositide-3-kinase, class 2, beta polypeptide
- phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Synonyms
- C2-PI3K
- PI3K-C2beta
GenBank acession
- Y11312
Locus

1q32.1
Discovery year

1998-05-21
Entrez gene record

5287
Pubmed identfication
- 9144573
- 9830063
RefSeq identity
- NM_002646
Classification
- Phosphatidylinositol 3-kinase subunits
VEGA ID

OTTHUMG00000036101

Identity

HGNC:13574
Gene

MAGEC2
Long gene name

MAGE family member C2
Synonyms gene
- MAGEE1
Synonyms gene name
- melanoma antigen, family E, 1, cancer/testis specific
- melanoma antigen family C2
Synonyms
- CT10
- MAGE-C2
- HCA587
Synonyms name
- cancer/testis antigen 10
GenBank acession
- AF116195
Locus

Xq27.2
Discovery year

2000-09-26
Entrez gene record

51438
Pubmed identfication
- 10699956
- 20864041
RefSeq identity
- NM_016249
Classification
- MAGE family
VEGA ID

OTTHUMG00000022574
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:4921
Gene

HIVEP2
Long gene name

HIVEP zinc finger 2
Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 2
- human immunodeficiency virus type I enhancer binding protein 2
Synonyms
- MBP-2
- HIV-EP2
- MIBP1
- ZAS2
- Schnurri-2
- ZNF40B
Synonyms name
- c-myc intron binding protein 1
GenBank acession
- M60119
Locus

6q24.2
Discovery year

1992-10-21
Entrez gene record

3097
Pubmed identfication
- 1733857
- 2022670
Classification
- Zinc fingers C2H2-type
VEGA ID

OTTHUMG00000015713

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325