MLL FISH Probe

Description

any of various testing devices or substances as (1) a pointed metal tip for making electrical contact with a circuit element being checked (2) a usually small object that is inserted into something so as to test conditions at a given point (3) a device used to penetrate or send back information especially from outer space or a celestial body (4) a device (as an ultrasound generator) or a substance (as radioactively labeled DNA) used to obtain specific information for diagnostic or experimental purposes

Gene target

MLL FISH
Gene symbol

SH3PXD2A, KMT2A
Short name

MLL FISH Probe
Technique

probe, probes
Species

Fish, Fishes
Alternative name

myeloid/lymphoid and mixed-lineage leukemia (trithorax homolog, Drosophila) fluorescence-emitting hybridization Probe
Alternative technique

probes
Alternative to gene target

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), ALL-1 and CXXC7 and HRX and HTRX1 and MLL and MLL/GAS7 and MLL1 and MLL1A and TET1-MLL and TRX1 and WDSTS, MLL and IDBG-73725 and ENSG00000118058 and 4297, lysine-acetylated histone binding, nuclei, Mll1 and IDBG-158453 and ENSMUSG00000002028 and 214162, MLL and IDBG-631302 and ENSBTAG00000018093 and 508330

Identity

HGNC:7132
Gene

KMT2A
Long gene name

lysine methyltransferase 2A
Synonyms gene
- MLL
Synonyms gene name
- myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog)
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
- lysine (K)-specific methyltransferase 2A
Synonyms
- TRX1
- HRX
- ALL-1
- HTRX1
- CXXC7
- MLL1A
Synonyms name
- Histone-lysine N-methyltransferase 2A
GenBank acession
- L04284
Locus

11q23.3
Discovery year

1991-11-15
Entrez gene record

4297
Pubmed identfication
- 1720549
RefSeq identity
- NM_005933
Classification
- PHD finger proteins
- SET domain containing
- Lysine methyltransferases
- Zinc fingers CXXC-type
- Bromodomain containing
VEGA ID

OTTHUMG00000166337
Locus Specific Databases
- LRG_613

Name

In Situ Hybridization, Fluorescence
Concept

Scope note: A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.
Tree numbers
- E01.370.225.500.620.670.325.350
- E01.370.225.750.600.670.325.350
- E05.200.500.620.670.325.350
- E05.200.750.600.670.325.350
- E05.393.285.350
- E05.393.661.475.350
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data