PCI-32765, BTK Inhibitor

Use

PCI-32765, BTK Inhibitor is used in laboratories on a frequent basis.
Ordering

the reference is 607-A3001-50MG for ordering
Reference

Gentaur can give you references of users of PCI-32765, BTK Inhibitor in your area. Call us on 00 32 265 09 23 for more information on 607-A3001-50MG
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

PCI-32765 BTK Inhibitor
Gene symbol

SERPINA5, BTK
Short name

PCI-32765, BTK Inhibitor
Alternative name

PCI-32765, Bruton agammaglobulinemia tyrosine kinase suppressor
Alternative to gene target

Bruton agammaglobulinemia tyrosine kinase, AGMX1 and AT and ATK and BPK and IMD1 and PSCTK1 and XLA, BTK and IDBG-79651 and ENSG00000010671 and 695, phosphatidylinositol-3, nuclei, Btk and IDBG-171427 and ENSMUSG00000031264 and 12229, BTK and IDBG-633447 and ENSBTAG00000019250 and 533459

Identity

HGNC:8723
Gene

SERPINA5
Long gene name

serpin family A member 5
Synonyms gene
- PLANH3
- PCI
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Synonyms
- PAI3
- PROCI
Synonyms name
- Protein C inhibitor
GenBank acession
- M68516
Locus

14q32.13
Discovery year

1992-10-02
Entrez gene record

5104
Pubmed identfication
- 1714450
- 8381582
- 24172014
RefSeq identity
- NM_000624
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000170860
Locus Specific Databases
- LRG_644

Identity

HGNC:1133
Gene

BTK
Long gene name

Bruton tyrosine kinase
Synonyms gene
- AGMX1
- IMD1
Synonyms gene name
- Bruton agammaglobulinemia tyrosine kinase
Synonyms
- ATK
- XLA
- PSCTK1
Synonyms name
- Bruton's tyrosine kinase
GenBank acession
- AK057105
Locus

Xq22.1
Discovery year

1986-01-01
Entrez gene record

695
Pubmed identfication
- 8380905
RefSeq identity
- NM_000061
Classification
- Tec family tyrosine kinases
- SH2 domain containing
- Pleckstrin homology domain containing
VEGA ID

OTTHUMG00000022022
Locus Specific Databases