eLUCidate RAW 264.7, TNF-a Reporter Cell Line

Description

eLUCidate RAW 264.7, TNF-a Reporter Cell Line expresses Renilla luciferase reporter gene under the transcriptional control of the TNF- promoter.
Similar product
Shipping

Dry ice
Storage

Liquid nitrogen
Shelflife

Use before expiry date given on the label
Contents

eLUCidate™ RAW 264.7, TNF- Reporter Cell Line
Amount

2-3 x 106 cells in 1 ml 90% FBS, 10% DMSO
Technical data
Data sheet

Contact us to request a Data sheet
Ordering

To order eLUCidate RAW 264.7, TNF-a Reporter Cell Line, please use the Cat. Nr.EL-TNFARAW and submit your purchase order by email or by fax. A discount is available for larger or bulk quantities, please contact us for more information
Tips

Our specialists recommend you to follow carefully the pre-registered instructions for eLUCidate RAW 264.7, TNF-a Reporter Cell Line
Additional description

For cells, cell lines and tissues in culture till half confluency.
Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

Gene target

eLUCidate RAW 264 TNF-a Reporter Line
Gene symbol

TNF, TNFRSF1A, TNFRSF1B, LTBR
Short name

eLUCidate RAW 264 7, TNF-a Reporter Line
Alternative name

eLUCidate RAW 264.7, tumor necrosis factor-a detector cellular Line
Alternative to gene target

tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
Tissue

cell

Identity

HGNC:11916
Gene

TNFRSF1A
Long gene name

TNF receptor superfamily member 1A
Synonyms gene
- TNFR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
Synonyms
- TNF-R
- TNFAR
- TNFR60
- TNF-R-I
- CD120a
- TNF-R55
GenBank acession
- M75866
Locus

12p13.31
Discovery year

1991-01-15
Entrez gene record

7132
Pubmed identfication
- 1655358
- 2158863
RefSeq identity
- NM_001065
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
VEGA ID

OTTHUMG00000168267
Locus Specific Databases
- INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
- LRG_193

Identity

HGNC:11917
Gene

TNFRSF1B
Long gene name

TNF receptor superfamily member 1B
Synonyms gene
- TNFR2
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
Synonyms
- TNFBR
- TNFR80
- TNF-R75
- TNF-R-II
- p75
- CD120b
GenBank acession
- M32315
Locus

1p36.22
Discovery year

1991-01-15
Entrez gene record

7133
Pubmed identfication
- 2158863
- 8702885
RefSeq identity
- NM_001066
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000001829