Protease Inhibitor Cocktail (100X; PI-1)

CAS number

N/A
Storage recommendations

-20°C
Shipping information

Shipped on next working day. Delivery information at order time
Technical documentation

For Manual, Protocol or Datasheet please contact us.
Dangerous contents

Harmful
Other products
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

Protease Inhibitor Cocktail 100X PI-1
Gene symbol

SERPINA1, SERPINF2, PDIA3, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1
Short name

Protease Inhibitor Cocktail (100X; PI-1)
Alternative name

Protease suppressor Cocktail (100X; PI-1)

Identity

HGNC:8941
Gene

SERPINA1
Long gene name

serpin family A member 1
Synonyms gene
- PI
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Synonyms
- AAT
- A1A
- PI1
- alpha-1-antitrypsin
- A1AT
- alpha1AT
Synonyms name
GenBank acession
- X01683
Locus

14q32.13
Discovery year

1986-01-01
Entrez gene record

5265
Pubmed identfication
- 24172014
RefSeq identity
- NM_001002235
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000150355
Locus Specific Databases
- LRG_575

Identity

HGNC:9075
Gene

SERPINF2
Long gene name

serpin family F member 2
Synonyms gene
- PLI
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
- serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Synonyms
- API
- ALPHA-2-PI
- A2AP
- AAP
- alpha2AP
Synonyms name
- alpha-2-plasmin inhibitor
- alpha-2-antiplasmin
GenBank acession
- D00174
Locus

17p13.3
Discovery year

1989-04-14
Entrez gene record

5345
Pubmed identfication
- 3416655
- 24172014
RefSeq identity
- NM_000934
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000090552
Locus Specific Databases
- LRG_885

Identity

HGNC:4606
Gene

PDIA3
Long gene name

protein disulfide isomerase family A member 3
Synonyms gene
- GRP58
Synonyms gene name
- glucose regulated protein, 58kDa
- protein disulfide isomerase-associated 3
- protein disulfide isomerase family A, member 3
Synonyms
- P58
- ERp61
- ERp57
- ERp60
- GRP57
- PI-PLC
- HsT17083
Locus

15q15.3
Discovery year

1997-06-09
Entrez gene record

2923
Pubmed identfication
- 8974399
RefSeq identity
- NM_005313
Classification
- Protein disulfide isomerases
VEGA ID

OTTHUMG00000044444

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081