TRAIL Receptor 2 protein

• Catalog number
  30R-AS051
• Price
  Please ask
• Size
  50 µg

• Category
  Proteins
• Antibody Subtype
  Recombinant Proteins
• Area of research
  Cell Cycle & Cell Death
• Reactivity
  Human
• Residues
  Region of TRAIL Receptor 2 protein corresponding to amino acids MESALITQQD LAPQQRVAPQ QKRSSPSEGL CPPGHHISED GRDCISCKYG QDYSTHWNDL LFCLRCTRCD SGEVELSPCT TTRNTVCQCE EGTFREEDSP EMCRKCRTGC PRGMVKVGDC TPWSDIECVH KES.
• Type of protein
  Recombinant
• Expression System
  Escherichia coli
• Grade Purity
  Grater than 98% pure
• Form Buffer
  Provided as a lyophilized powder.
• Storage
  Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• Shipping conditions
  Blue Ice
• Tested for
  Please refer to the datasheet
• Bioactivity
  Determined by its inhibitory effect of IL-8 production in human PBMC by human sTRAIL/Apo2L. 50% inhibition (100 ng/ml of sTRAIL/Apo2L) was reached using a concentration of 1000 ng/ml of sTRAIL Receptor-2.
• URL
• More info
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TRAIL   Receptor   protein  
• Gene symbol
  TNFSF10, TNFRSF10B
• Short name
  TRAIL Receptor 2 protein
• Alternative name
  Purified recombinant Human TRAIL Receptor 2 protein

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

Similar products