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Applications
WB, IHC
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Product Type
Primary Antibodies
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Product Subtype
Purified Polyclonal Antibodies
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Research Area
Cytokines & Growth Factors
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Immunogen
NFkB p65 antibody was raised in Rabbit using a synthesized non-phosphopeptide derived from human NFkB p65 around the phosphorylation site of serine 468 (L-A-SP-V-D) as the immunogen.
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Specificity
NFkB p65 antibody detects endogenous levels of total NFkB p65 protein
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Cross Reactivity
Mouse, Rat
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Clone
NA
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Concentration
1 mg/ml
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Form Buffer
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
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Storage
Store at -20 deg C in small aliquots. Avoid repeat freeze/thaw cycles
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Shipping Info
Blue Ice
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Properties
If you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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About
Rabbits are used for polyclonal antibody production by fitzgerald. Rabbit antibodies are very stable and can be stored for several days at room temperature. fitzgerald adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps