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Category
Proteins
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Antibody Subtype
Recombinant Proteins
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Area of research
Differentiation & Development
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Reactivity
Human
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Residues
Region of Noggin protein corresponding to amino acids QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC.
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Type of protein
Recombinant
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Expression System
293 cells
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Grade Purity
Grater than 98% pure
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Form Buffer
Provided lyophilized with no additives. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
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Storage
Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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Shipping conditions
Blue Ice
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Tested for
Please refer to the datasheet
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Bioactivity
Determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin.
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