NFkB p105 subunit protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

DNA & RNA
Reactivity

Human
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 90% pure
Form Buffer

Provided in liquid form in PBS buffer with 20 mM GSH
Storage

Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles
Tested for

ELISA; SDS-PAGE; WB
URL
More info
Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory