Klotho protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Nutrition & Metabolism
Reactivity

Human
Residues

Region of Klotho protein corresponding to amino acids EPGDGAQTWA RFSRPPAPEA AGLFQGTFPD GFLWAVGSAA YQTEGGWQQH GKGASIWDTF THHPLAPPGD SRNASLPLGA PSPLQPATGD VASDSYNNVF RDTEALRELG VTHYRFSISW ARVLPNGSAG VPNREGLRYY RRLLERLREL GVQPVVTLYH WDLPQRLQDA YGGWANRALA DHFRDYAELC FRHFGGQVKY WITIDNPYVV AWHGYATGRL APGIRGSPRL GYLVAHNLLL AHAKVWHLYN TSFRPTQGGQ VSIALSSHWI NPRRMTDHSI KECQKSLDFV LGWFAKPVFI DGDYPESMKN NLSSILPDFT ESEKKFIKGT ADFFALCFGP TLSFQLLDPH MKFRQLESPN LRQLLSWIDL EFNHPQIFIV ENGWFVSGTT KRDDAKYMYY LKKFIMETLK AIKLDGVDVI GYTAWSLMDG FEWHRGYSIR RGLFYVDFLS QDKMLLPKSS ALFYQKLIEK NGFPPLPENQ PLEGTFPCDF AWGVVDNYIQ VSQLTKPISS LTKPYH.
Type of protein

Recombinant
Expression System

CHO cells
Grade Purity

Grater than 98% pure
Form Buffer

Provided as a lyophilized powder.
Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Tested for

Please refer to the datasheet
Bioactivity

Determined by the dose-dependent stimulation of the proliferation of Mouse NIH-3T3 cells. Recombinant human Klotho is effective in a concentration range of 0.5-2.0 ug/ml.
URL
More info

Identity

HGNC:19069
Gene

GBA3
Long gene name

glucosylceramidase beta 3 (gene/pseudogene)
Synonyms gene name
- glucosidase, beta, acid 3 (cytosolic)
- glucosidase, beta, acid 3 (gene/pseudogene)
Synonyms
- GLUC
- KLrP
- CBGL1
Synonyms name
- klotho-related protein
- cytosolic β-glucosidase-like protein-1
GenBank acession
- AB017913
Locus

4p15.2
Discovery year

2002-12-16
Entrez gene record

57733
Pubmed identfication
- 11389701
- 17595169
Classification
- Glycoside hydrolase family 1
VEGA ID

OTTHUMG00000160448