IL2R alpha protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Cytokines & Growth Factors
Reactivity

Human
Residues

Region of IL2 protein corresponding to amino acids ELCDDDPPEI PHATFKAMAY KEGTMLNCEC KRGFRRIKSG SLYMLCTGNS SHSSWDNQCQ CTSSATRNTT KQVTPQPEEQ KERKTTEMQS PMQPVDQASL PGHCREPPPW ENEATERIYH FVVGQMVYYQ CVQGYRALHR GPAESVCKMT HGKTRWTQPQ LICTGEMETS QFPGEEKPQA SPEGRPESET SCLVTTTDFQ IQTEMAATME TSIFTTEYQ.
Type of protein

Recombinant
Expression System

CHO cells
Grade Purity

Grater than 98% pure
Form Buffer

Lyophilized from PBS. Reconstitute with PBS, pH 7.2 to a concentration of 0.1 - 1.0 mg/ml.
Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Tested for

Please refer to the datasheet
Bioactivity

Determined by its ability to increase the proliferation effect of IL-2 in Mouse CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5 - 1.5 ug/ml.
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More info
Description

The IL2R alpha protein is a α- or alpha protein sometimes glycoprotein present in blood.

Identity

HGNC:6008
Gene

IL2RA
Long gene name

interleukin 2 receptor subunit alpha
Synonyms gene
- IL2R
- IDDM10
Synonyms gene name
- insulin-dependent diabetes mellitus 10
- interleukin 2 receptor, alpha
Synonyms
- CD25
GenBank acession
- X01057
Locus

10p15.1
Discovery year

1990-01-22
Entrez gene record

3559
Pubmed identfication
- 3925551
- 17676041
RefSeq identity
- NM_000417
Classification
- CD molecules
- Sushi domain containing
- Interleukin receptors
VEGA ID

OTTHUMG00000017616
Locus Specific Databases
- IL2RAbase: Mutation registry for Interleuken 2 receptor α deficiency
- LRG_73