Hepatitis C Virus protein chimera

Product Type

Proteins
Product Subtype

Recombinant Proteins
Research Area

Infectious Disease
Tag Conjugate

Contains four antigens expressed in E. coli in a chimera: HCV Core Fragment (a.a. 11-45); HCV NS3 Fragment (a.a. 1208-1430); HCV NS4 Fragment (a.a. 1885-1923); HCV NS5 Fragment (a.a. 2332-2423). Also contains a fusion protein.
Type1

NA
Form Buffer

Supplied in liquid form in 20 mM Phosphate Buffer, pH 7.4
Storage

Store < 2 weeks at 2-8 deg C. Long term store at -20 deg C. Aliquot to avoid multiple freeze/thaw cycles
Applications

NA
Shipping Info

Blue Ice
Description

Hepatitis a, b, c, d, e recombinant surface viral antigens to genotype 1, 2, 3, 4, 5 are used for antibody production to make diagnostic poly or monoclonal antibodies. Hepatitis is a disease of the liver characterized by the presence of inflammatory cells in the tissue of the organ. Hepatitis may occur without symptoms, but can lead to jaundice (a yellow discoloration of the skin, mucous membranes, and conjunctiva of the eyes), poor appetite, and fatigue. Depending on the cause, hepatitis can manifest either as an acute or as a chronic disease.

Gene target

Hepatitis Virus protein
Gene symbol

FAM174A
Short name

Hepatitis C Virus protein
Technique

Fc chimeras and Chimera RNAi's are part non target species constructions.
Species

Virus, Viruses
Alternative name

Hepatitis C Virus protein chimera
Virus

hepatitis

Identity

HGNC:24943
Gene

FAM174A
Long gene name

family with sequence similarity 174 member A
Synonyms gene
- TMEM157
Synonyms gene name
- transmembrane protein 157
- family with sequence similarity 174, member A
Synonyms
- UNQ1912
- NS5ATP6
Synonyms name
- hepatitis C virus nonstructural protein 5A trans-activated protein 6
GenBank acession
- AY359108
Locus

5q21.1
Discovery year

2006-05-23
Entrez gene record

345757
Pubmed identfication
- 12975309
RefSeq identity
- NM_198507
VEGA ID

OTTHUMG00000128726