GDF5 protein

Category

Proteins
Antibody Subtype

Recombinant Proteins
Area of research

Cytokines & Growth Factors
Reactivity

Human
Residues

GDF5 protein containing region of amino acids corresponding to: APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR.
Type of protein

Recombinant
Expression System

Escherichia coli
Grade Purity

Grater than 98% pure
Form Buffer

Provided as a lyophilized powder.
Storage

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping conditions

Blue Ice
Tested for

Please refer to the datasheet
Bioactivity

Induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 40Nm.
Assay Information

Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 1.15 as the extinction coefficient for a 0.1% (1mg/ml) solution. 2. Analysis by RP-HPLC, using a standard solution of GDF5 as a Reference Standard.
URL
More info

Gene target

GDF5 protein
Gene symbol

GDF5, GDF5-AS1
Short name

GDF5 protein
Alternative name

Purified recombinant Human GDF5 protein
Alternative to gene target

growth differentiation factor 5, BDA1C and BMP-14 and BMP14 and CDMP1 and LAP-4 and LAP4 and OS5 and SYM1B and SYNS2, GDF5 and IDBG-70038 and ENSG00000125965 and 8200, growth factor activity, Extracellular, Gdf5 and IDBG-210734 and ENSMUSG00000038259 and 14563, BT.86382 and IDBG-642165 and ENSBTAG00000004429 and 539559

Identity

HGNC:4220
Gene

GDF5
Long gene name

growth differentiation factor 5
Synonyms
- CDMP1
- BMP14
Synonyms name
- cartilage-derived morphogenetic protein-1
GenBank acession
- X80915
Locus

20q11.22
Discovery year

1997-12-05
Entrez gene record

8200
Pubmed identfication
- 9288091
- 9288098
Classification
- Transforming growth factor beta superfamily
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000032341