Caspase 8 antibody

• Catalog number
  70R-11657
• Price
  Please ask
• Size
  100 µg

• Category
  Primary Antibody
• Antibody Subtype
  Polyclonal Antibodies, Purified
• Area of research
  Proteases, Inhibitors, & Enzymes
• Type of Immunogen
  Caspase 8 antibodies were raised in Rabbit using synthetic peptide surrounding the cleavage site of human Caspase-8 ..
• Raised in
  Rabbit
• Cross Reactivity
  Human
• Isotypes
  IgG
• Method of Purification
  Caspase 8 antibody was purified by affinity chromatography
• Concentration
  500 ug/ml
• Form Buffer
  Provided in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
• Storage
  Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• Shipping conditions
  Blue Ice
• Tested for
  IHC; WB
• Usage Recommendations
  IHC: 10-20 mg/ml, WB: 0.5-4 ug/ml
• Assay Information
  Caspase 8 Blocking Peptide, catalog no. 33R-10652, is also available for use as a blocking control in assays to test for specificity of this Caspase 8 antibody
• URL
• More info
• Properties
  If you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
• French translation
  anticorps

• Gene target
  Caspase  
• Gene symbol
  CASP8, CARD8, CASP8AP2
• Short name
  Caspase 8 antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Rabbit polyclonal Caspase 8 antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1509
• Gene
  CASP8
• Long gene name
  caspase 8
• Synonyms gene name
  • caspase 8, apoptosis-related cysteine protease
  • caspase 8, apoptosis-related cysteine peptidase
• Synonyms
  • MCH5
  • MACH
  • FLICE
  • Casp-8
• GenBank acession
  • U60520
• Locus
  2q33.1
• Discovery year
  1996-11-11
• Entrez gene record
  841
• Pubmed identfication
  • 8681376
  • 8681377
• RefSeq identity
  • NM_001228
• Classification
  • Caspases
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000132821
• Locus Specific Databases
  • CASP8base: Mutation registry for Caspase 8 deficiency
  • LRG_34

Gene info

• Identity
  HGNC:17057
• Gene
  CARD8
• Long gene name
  caspase recruitment domain family member 8
• Synonyms gene name
  • caspase recruitment domain family, member 8
• Synonyms
  • TUCAN
  • KIAA0955
  • CARDINAL
  • NDPP
  • Dakar
• GenBank acession
  • AB023172
• Locus
  19q13.33
• Discovery year
  2003-12-03
• Entrez gene record
  22900
• Pubmed identfication
  • 10231032
  • 11408476
• RefSeq identity
  • NM_014959
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000165047

Gene info

• Identity
  HGNC:1510
• Gene
  CASP8AP2
• Long gene name
  caspase 8 associated protein 2
• Synonyms gene name
  • CASP8 associated protein 2
• Synonyms
  • FLASH
  • CED-4
  • RIP25
  • FLJ11208
  • KIAA1315
• Synonyms name
  • FLICE-associated huge protein
• GenBank acession
  • AB037736
• Locus
  6q15
• Discovery year
  1999-12-10
• Entrez gene record
  9994
• Pubmed identfication
  • 10235259
  • 17245429
  • 17003126
• RefSeq identity
  • NM_001137667
• VEGA ID
  OTTHUMG00000015212

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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