anti- SKAP2 antibody

• Catalog number
  FNab07890
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Immunogen
  src kinase associated phosphoprotein 2
• Synonyms
  PRAP, RA70, SAPS, SCAP2, SKAP55R
• Calculated MW
  Refer to Figures
• Uniprot ID
  O75563
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab07890( SKAP2 Antibody) at dilution of 1:200
• Image4
  human liver tissue were subjected to SDS PAGE followed by western blot with FNab07890(SKAP2 antibody) at dilution of 1:1500
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SKAP2  
• Gene symbol
  SKAP2
• Short name
  anti- SKAP2 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) kinase associated phosphoprotein 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  src kinase associated phosphoprotein 2, PRAP and RA70 and SAPS and SCAP2 and SKAP-HOM and SKAP55R, SKAP2 and IDBG-10241 and ENSG00000005020 and 8935, protein binding, nuclei, Skap2 and IDBG-147582 and ENSMUSG00000059182 and 54353, SKAP2 and IDBG-633609 and ENSBTAG00000005650 and 616545

Gene info

• Identity
  HGNC:15687
• Gene
  SKAP2
• Long gene name
  src kinase associated phosphoprotein 2
• Synonyms gene
  • SCAP2
• Synonyms gene name
  • src family associated phosphoprotein 2
• Synonyms
  • RA70
  • SKAP-HOM
  • SKAP55R
  • SAPS
• Locus
  7p15.2
• Discovery year
  2001-07-19
• Entrez gene record
  8935
• Pubmed identfication
  • 9837776
  • 9755858
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000023495

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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