anti- PARN antibody

• Catalog number
  FNab06150
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Immunogen
  poly(A)-specific ribonuclease (deadenylation nuclease)
• Synonyms
  DAN
• Calculated MW
  75 kDa
• Uniprot ID
  O95453
• Specificity
  Human
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:1000 - 1:3000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab06150(PARN antibody) at dilution of 1:100
• Image4
  MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab06150(PARN antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PARN  
• Gene symbol
  PARN
• Short name
  anti- PARN antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- PARN (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8609
• Gene
  PARN
• Long gene name
  poly(A)-specific ribonuclease
• Synonyms gene name
  • poly(A)-specific ribonuclease (deadenylation nuclease)
• Synonyms
  • DAN
• Synonyms name
  • deadenylation nuclease
• GenBank acession
  • AJ005698
• Locus
  16p13.12
• Discovery year
  1998-07-23
• Entrez gene record
  5073
• Pubmed identfication
  • 10640832
• RefSeq identity
  • NM_002582
• Classification
  • Ribosomal biogenesis factors
  • PARN exonuclease family
• VEGA ID
  OTTHUMG00000173199
• Locus Specific Databases
  • LRG_1286

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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