anti- KLC1 antibody

• Catalog number
  FNab04594
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.
• Immunogen
  kinesin light chain 1
• Synonyms
  KLC, KNS2
• Calculated MW
  66 kDa
• Uniprot ID
  Q07866
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human brain using FNab04594(KLC1 antibody) at dilution of 1:100
• Image4
  mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04594(KLC1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KLC1  
• Gene symbol
  KLC1
• Short name
  anti- KLC1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- KLC1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6387
• Gene
  KLC1
• Long gene name
  kinesin light chain 1
• Synonyms gene
  • KNS2
• Synonyms gene name
  • kinesin 2 60/70kDa
  • kinesin 2
• Synonyms
  • KNS2A
  • KLC
  • hKLC1S
  • hKLC1N
  • hKLC1P
  • hKLC1G
  • hKLC1R
  • hKLC1J
  • hKLC1B
• GenBank acession
  • AF267530
• Locus
  14q32.33
• Discovery year
  1994-07-07
• Entrez gene record
  3831
• Pubmed identfication
  • 8274221
  • 11106729
• RefSeq identity
  • NM_005552
• Classification
  • Tetratricopeptide repeat domain containing
• VEGA ID
  OTTHUMG00000169227

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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