anti- Cardiac Troponin I antibody

• Catalog number
  FNab01273
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
• Immunogen
  troponin I type 3 (cardiac)
• Synonyms
  Cardiac troponin I, cTnI, RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle
• Calculated MW
  Refer to figures
• Uniprot ID
  P19429
• Specificity
  Human, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human heart using FNab01273(TNNI3 antibody) at dilution of 1:50
• Image4
  rat heart tissue were subjected to SDS PAGE followed by western blot with FNab01273( TNNI3 Antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cardiac   Troponin  
• Gene symbol
  TNNI3
• Short name
  anti- Cardiac Troponin I antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- Cardiac Troponin I (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11947
• Gene
  TNNI3
• Long gene name
  troponin I3, cardiac type
• Synonyms gene
  • CMD2A
• Synonyms gene name
  • cardiomyopathy, dilated 2A (autosomal recessive)
  • troponin I type 3 (cardiac)
  • troponin I type 3
• Synonyms
  • TNNC1
  • CMH7
• GenBank acession
  • M64247
• Locus
  19q13.42
• Discovery year
  1989-12-11
• Entrez gene record
  7137
• Pubmed identfication
  • 9605869
  • 9241277
  • 10806205
• Classification
  • Troponin complex subunits
• VEGA ID
  OTTHUMG00000180589
• Locus Specific Databases
  • FHC Mutation Database
  • LRG_432

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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