anti- CAPNS1 antibody
-
Catalog numberFNab01250
-
PricePlease ask
-
Size2X100μg
-
-
Formliquid
-
PurificationImmunogen affinity purified
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
BackgroundThis gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.
-
Immunogencalpain, small subunit 1
-
SynonymsCAPN4, CAPNS
-
Calculated MW25 kDa
-
Uniprot IDP04632
-
SpecificityHuman, Mouse, Rat
-
Tested ApplicationELISA, WB, IHC
-
Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200
-
Image1Immunohistochemistry of paraffin-embedded human stomach tissue slide using FNab01250( CAPNS1 Antibody) at dilution of 1:50
-
Image4HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01250( CAPNS1 Antibody) at dilution of 1:1000
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
-
PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCAPNS1
-
Short nameanti- CAPNS1 antibody
-
TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
-
HostRabbit
-
IsotypeIgG
-
Alternative nameantibody to- CAPNS1 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namecalpain small subunit 1
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1989-06-30
-
Entrez gene record
-
Pubmed identfication
-
Classification
- EF-hand domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data