anti- BRAF antibody

• Catalog number
  FNab00941
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
• Immunogen
  v-raf murine sarcoma viral oncogene homolog B1
• Synonyms
  BRAF1, RAFB1
• Calculated MW
  98 kDa
• Uniprot ID
  P15056
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human malignant melanoma tissue slide using FNab00941( BRAF Antibody) at dilution of 1:200
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BRAF  
• Gene symbol
  BRAF
• Short name
  anti- BRAF antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- v-raf murine sarcoma viral oncogene homolog B1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  v-raf murine sarcoma viral oncogene homolog B1, B-RAF1 and BRAF1 and NS7 and RAFB1, BRAF and IDBG-44351 and ENSG00000157764 and 673, transferase activity, nuclei, Braf and IDBG-138657 and ENSMUSG00000002413 and 109880, BRAF and IDBG-636391 and ENSBTAG00000021761 and

Gene info

• Identity
  HGNC:1097
• Gene
  BRAF
• Long gene name
  B-Raf proto-oncogene, serine/threonine kinase
• Synonyms gene name
  • v-raf murine sarcoma viral oncogene homolog B
• Synonyms
  • BRAF1
• GenBank acession
  • M95712
• Locus
  7q34
• Discovery year
  1991-07-16
• Entrez gene record
  673
• Pubmed identfication
  • 2284096
  • 1565476
• RefSeq identity
  • NM_004333
• Classification
  • Mitogen-activated protein kinase kinase kinases
  • RAF family
• VEGA ID
  OTTHUMG00000157457
• Locus Specific Databases
  • LRG_299

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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